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The DNA Laboratories Genetic Disorders Assessment Center Molecular Cytogenetics Laboratory covers the application of molecular cytogenetic methods, including structural and functional organization of the chromosome and nucleus, genome variation, expression, and evolution, chromosome abnormalities, and medical genetic and genomic variations.
Molecular cytogenetics describes a large number of methods that work primarily with the whole genome or specifically targeted DNA. Some areas are as follows, but are not limited to:
- Structural and functional organization of the chromosome and nucleus
- Genome variation, expression, and evolution
- Chromosome abnormalities and genomic variations in clinical genetics
- Pre-implantation, prenatal, and postnatal diagnostic applications
- Cancer and hematology research
DNA Laboratories Molecular Cytogenetics Laboratory is managed by our Genetics Specialists and has Molecular Cytogenetics Laboratory manager and laboratory personnel with relevant license degrees.
DNA Laboratories use the latest technologies in molecular cytogenetics methods in fluorescence in situ hybridization (FISH) analysis for a wide range of clinical environments from prenatal and postnatal diagnosis to cancer.
Services
We perform diagnostic procedures such as cytogenetics, molecular cytogenetics, and molecular pathology in leukemias, lymphomas, and solid tumors.
Prenatal/postnatal diagnosis of microdeletion syndromes and numerical aberrations.
Prenatal
Rapid fluorescence in situ hybridization (FISH) for aneuploidy screening.
Interphase analysis for the aneuploids of chromosomes 13, 18, 21, X, and Y enables the rapid detection of the most common chromosomal aneuploids. We can run these scans on chorionic villi or amniotic fluid.
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Solid Tumor FISH
ALK, ROS, HER2, PDL1, cMET
Oncological FISH
- Acute Lymphocytic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Myelodysplastic Syndrome (MDS)
- Multiple Myeloma
- Chronic Myeloid Leukemia (CML)
- Non-Hodgkin Lymphoma
- Chronic Lymphocytic Leukemia (CLL)
You can review our test list or contact us for further information and panel contents about the tests.
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