Our ServicesPre-implantation Genetic Diagnosis


Pre-implantation genetic diagnosis (PGT) is a genetic test of embryos before they are transferred to the uterus. PGT is recommended for couples at risk of a genetic disorder or anomaly. Only healthy embryos are transferred to the mother by the PGT test.

Pre-implantation Genetic Screening (PGT-A) is the screening of embryos with various methods for aneuploids (numerical chromosomal disorders) in healthy genetically structured couples.

If the couple’s close or distant relatives are known to have a single gene disorder or a disorder caused by a change in a single gene, they may be at risk of having that genetic disorder in the child to be born. Pre-implantation Genetic Test (PGT-M) in single-gene disorders is used to reduce the risk of passing down such disorders to the next generations.

It stands out as an important alternative to invasive prenatal diagnostic methods (amniocentesis or chorionic villus) as healthy and unaffected embryos are transferred with PGT-M and PGT-A. PGT-M and PGT-A save families from a difficult situation such as termination of pregnancy when invasive prenatal diagnosis yields negative results. PGT-M and PGT-A are the only tests to prevent the risk of giving birth to a child with a disorder.

To Whom Pre-implantation Genetic Diagnosis Be Performed?

Prospective mothers of advanced age,

Couples with recurrent miscarriages

Couples experiencing recurrent implantation failure,

Advanced male infertility factor,

A single gene disorder or disorders caused by a single gene change in close or distant relatives of the couple,

In HLA compliance screenings,

Couples who previously had children with genetic disorders,

Indications for Pre-implantation Genetic Diagnosis

a) Sex chromosome-related diseases
b) Single-gene disorders
c) HLA (Human leukocyte antigen) compliance screening
d) Chromosomal disorders

“In our DNA Laboratories Genetic Disorders Assessment Center, numerical and structural chromosomal anomalies are detected by Next Generation Sequencing (NGS), single-gene disorders and HLA compliance screenings, Next Generation Sequencing, Sanger Sequencing, and Fragment Analysis methods.”

The size, timing, and price of the test to be performed after our Genetic Counseling Service, which will be given to the family for Pre-implantation Genetic Test PGT-M in Single Gene Disorders and HLA compliance screening, is determined.

Pre-implantation Genetic Screening (PGT-A) by Next Generation Sequencing (NGS) Method

The genome of embryos can be sequenced after amplification and can be used in the PGT-A process by determining chromosome aneuploids as a result of analysis of this data with this method called next-generation sequencing (NGS). Analyses performed by the NGS method provide advantageous, more detailed, and precise results compared to aCGH and other methods and can better determine the mosaicism rate in embryos. Due to these advantages, it has begun to be used as the most advanced method for PGT-A.

You can review our test list or contact us for further information and panel contents about the tests.

PGT-M Süreci 
Vaka Değerlendirme
Aday ebeveynler Genetik Uzmanımızla görüşerek, çiftin veya diğer aile üyelerinin ek genetik testinin gerekli olup olmadığı kararlaştırılır.
PTG-M Test Hazırlığı
Laboratuvarımızda aileye özgü PGT-M testi tasarlanır.
Tüp Bebek Merkezi
In vitro fertilizasyon yapılır ve oluşan embriyolar inkübe edilir.
Embriyo Biyopsisi
Embriyolog, her embriyodan dikkatlice örnek alır.
PGT-M Test Aşaması
Embriyolog tarafından alınan örnekler laboratuvarımıza gönderildikten sonra PGT-M testi yapılır ve sonuçlar Tüp Bebek Merkezi ile paylaşılır.
Embriyo Transferi
Etkilenmemiş embriyo transfer edilir, kalan embriyolar ileride kullanmak üzere dondurulabilir.

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Genetic Counseling
Genetic counseling is the process of acquiring information on genetic disorders.
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