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Cancer Genetics

ONCOSEQ DNALAB HERITAGE CANCER PANELS

ONCOSEQ DNALAB COMPREHENSIVE HERITAGE CANCER PANEL

Today, genetic tests for cancer are personalized; It is carried out for the diagnosis, follow-up, prognosis and treatment of oncological diseases, choosing the right drug and determining the risk of familial cancer. Disorders that cause cancer; Gene mutations, increased gene expression, deletions, translocations and similar anomalies are detected by genetic tests. Some DNA mutations are hereditary and are passed down through your family. This means that when you are born, mutations are in all your cells. These mutations can greatly increase the risk of certain cancers. They cause most of the cancers that occur in various members of some families, and often people with the genetic disorder can get cancer at a younger age.

WHY CHOOSE CENTOGENE?
  • Test:
    Hereditary Cancer Tests
  • Method:
    Next Generation Sequencing
  • Analysis Time:
    21 Days
  • Sample Type:
    Blood (with EDTA)
  • Storage Conditions:
    1 week at +4 C
  • Transport Conditions:
    The same day; At room temperature
  • Rejection Criteria:
    Hemolyzed, Lipemic, Icteric samples are not accepted

Gene Table

Comprehensive Hereditary Cancer Panel (160 Genes)
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BRCA2 EXT1 MAX PRKAR1A SUFU
BRIP1 EXT2 MEN1 PTCH1 TERC
BUB1B EZH2 MET PTEN TERT
CBL FANCA MITF PTPN11 TINF2
CDC73 FANCB MLH1 RAD50 TMEM127
AIP DIS3L2 GATA2 NSUN2 SDHB
ALK DKC1 GPC3 NTHL1 SDHC
ANKRD26 EGFR GREM1 PALB2 SDHD
APC ELANE HNF1A PAX5 SHOC2
ATM EPCAM HOXB13 PDGFRA SLX4
AXIN2 ERCC1 HRAS PHOX2B SMAD4
BAP1 ERCC2 IKZF1 PMS1 SMARCA4
BARD1 ERCC3 KIT PMS2 SMARCB1
BLM ERCC4 KITLG POLD1 SOS1
BMPR1A ERCC5 KRAS POLH SPRED1
BRAF ETV6 MAP2K1 PPM1D SRP72
BRCA1 EXO1 MAP2K2 PRF1 STK11
CDH1 FANCC MLH3 RAD51C TP53
CDK4 FANCD2 MRE11A RAD51D TSC1
CDKN1B FANCD2 MRE11A RAD51D TSC1
CDK4 FANCE MSH2 RAF1 TSC2
CDKN1C FANCF MSH3 RB1 VHL
CDKN2A FANCG MSH6 RECQL4 WRN
CEBPA FANCI MUTYH RET WT1
CEP57 FANCL NBN RHBDF2 XPA
CHEK2 FANCM NF1 RUNX1 XPC
CYLD FH NF2 SAMD9 XRCC2
DDB2 FLCN NRAS SDHA ERCC5
DICER1 GALNT12 NSD1 SDHAF2 ATR
PIK3CA

Hereditary Breast and Ovarian Cancer (27 Genes)
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ATM BARD1 BLM BRCA1 BRCA2
BRIP1 CDH1 CHEK2 DICER1 EPCAM
FANCM MLH1 MRE11A MSH2 MSH6
NBN NF1 PALB2 PMS2 PTEN
RAD50 RAD51C RAD51D SMARCA4 STK11
TP53 XRCC2

Hereditary Breast Cancer High Risk Panel (7 Genes)
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BRCA1 BRCA2 CDH1 PALB2 PTEN STK11 TP53

Hereditary Cancer High Risk Panel (27 Genes)
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APC ATM BAP1 BMPR1A BRCA1 BRCA2 CDH1 CDK4 CDKN2A
CHEK2 EPCAM MEN1 MLH1 MSH2 MSH6 MUTYH PALB2 PMS2
POLD1 PTEN RAD51C RAD51D RET SMAD4 STK11 TP53 VHL

Hereditary Colorectal Cancer Panel (19 Genes)
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APC AXIN2 BLM BMPR1A EPCAM GALNT12 GREM1 MLH1 MSH2 MSH3
MSH6 MUTYH NTHL1 PMS2 POLD1 PTEN SMAD4 STK11 TP53

Hereditary Endocrine Cancer Panel (22 Genes)
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AIP APC CDC73 CDKN1B DICER1 FH MAX MEN1 MET NF1 PRKAR1A
PTEN RET SDHA SDHAF2 SDHB SDHC SDHD TMEM127 TP53 VHL WRN

Hereditary Gastrointestinal Cancer Panel (40 Genes)
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APC ATM AXIN2 BLM BMPR1A
BRCA1 BRCA2 BUB1B CDH1 CDKN2A
EPCAM FANCC GALNT12 GREM1 KIT
MEN1 MLH1 MSH2 MSH3 MSH6
MUTYH NF1 NTHL1 PALB2 PDGFRA
SDHC SDHD SMAD4 SMARCB1 STK11
TMEM127 TP53 TSC1 TSC2 VHL

Hereditary Leukemia Panel (36 Genes)
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ANKRD26 ATM BLM BRAF BRCA1
BRCA2 CBL CDKN2A CEBPA DKC1
EPCAM ETV6 FANCA GATA2 HRAS
IKZF1 KRAS MAP2K1 MAP2K2 MLH1
MSH2 MSH6 NBN NF1 NRAS
PAX5 PMS2 PTPN11 RUNX1 SAMD9
SOS1 SRP72 TERC TERT TINF2 TP53

Hereditary Lung Cancer Panel (4 Genes)
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BRCA2 CDKN2A EGFR TP53

Hereditary Melanoma and Skin Cancer Panel (18 Genes)
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BAP1 BRCA1 BRCA2 CDK4 CDKN2A DDB2
ERCC2 ERCC3 ERCC4 ERCC5 MITF PTCH1
PTEN SUFU TP53 WRN XPA XPC

Hereditary Pancreatic Cancer Panel (22 Genes)
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APC ATM BMPR1A BRCA1 BRCA2
BUB1B CDKN2A EPCAM FANCC MEN1
MLH1 MSH2 MSH6 NF1 PALB2 PMS2
SMAD4 STK11 TP53 TSC1 TSC2 VHL

Hereditary Paraganglioma and Pheochromocytoma Panel (11 Genes)
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FH MAX NF1 RET SDHA
SDHAF2 SDHB SDHC SDHD TMEM127 VHL

Hereditary Pediatric Cancer Panel (65 Genes)
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ALK DIS3L2 MSH2 PTCH1 SMAD4
APC EPCAM MSH6 PTEN SMARCA4
AXIN2 EZH2 NBN PTPN11 SMARCB1
BAP1 FH NF1 RAF1 SOS1
BLM GATA2 NF2 RECQL4 STK11
BMPR1A GPC3 NRAS RET SUFU
BRAF HRAS NSD1 RUNX1 TMEM127
BUB1B KRAS NSUN2 SDHA TP53
CBL MAP2K1 PAX5 SDHAF2 TSC1
CDC73 MAP2K2 PHOX2B SDHB TSC2
CDKN1C MAX PMS2 SDHC VHL
CEBPA MEN1 PRF1 SDHD WRN
DICER1 MLH1 PRKAR1A SHOC2 WT1

Hereditary Renal Cancer Panel (25 Genes)
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BAP1 CDC73 CDKN1C DICER1 DIS3L2
EPCAM FH FLCN GPC3 MET
MLH1 MSH2 MSH6 PMS2 PTEN
SDHB SDHC SDHD SMARCA4 SMARCB1
TP53 TSC1 TSC2 VHL WT1

Tuberous Sclerosis Panel (2 Genes)
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TSC1 TSC2

Xeroderma Pigmentosum Panel (9 Genes)
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DDB2 ERCC1 ERCC2 ERCC3 ERCC4
ERCC5 POLH XPA XPC

Discover Your Genetic Heritage

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ONCOSEQ DNALAB (Cancer Genetics)

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Preimplantation Genetic Diagnosis (PGD)

Whole Exome Sequencing

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